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Catalyst

coenzyme Q10Finding

Coenzyme Q10 decreases tumour necrosis factor alpha concentration

lowersModerate evidenceFindingreplicated ×3

01 · The sentence it was drawn from

“Pooled analysis of five RCTs (100 participants in the CoQ10 groups and 94 in the control groups) showed that CoQ10 supplement significantly reduced TNF‐ α levels (SMD = −1.01; 95% CI: −1.56, −0.46; I 2 = 68.6 %; p = 0.013).”
Quoted verbatim from Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
This finding among the 70 findings on its endpoint

coenzyme Q10

Tumour necrosis factor alpha concentration

lowers

Effect as reported

−1.01standardised mean difference

CI −1.56 to −0.46

Who
Adults with disorders of lipid and/or glucose metabolism; five randomised trials pooled, CoQ10 alone or with co-interventions against a control receiving the same co-intervention
Dose studied
CoQ10 60 to 600 mg/day, pooled; 4 to 24 weeks

Moderate evidencePMID 42192187 · 2026

02 · The study

Study
meta-analysis
Duration
not reported

Evidence, by strength

  • strong
  • moderatethis finding
  • limited
  • very limited
  • insufficient

03 · The paper

Journal of diabetes research
What else it reported11 findings · 1 compound · 11 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6Y3PVXQT5XN611DD9JDMERP