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coenzyme Q10Finding

Coenzyme Q10 increases clinical pregnancy rate

raisesModerate evidenceFindingreplicated ×1

01 · The sentence it was drawn from

“The forest plot of intervention effects on IVF/ICSI outcomes suggested that CoQ10 pretreatment was efficacious in improving clinical pregnancy rate (OR = 1.84, 95%CI [1.33, 2.53], p = 0.0002, I2 = 29%).”
Quoted verbatim from Clinical evidence of coenzyme Q10 pretreatment for women with diminished ovarian reserve undergoing IVF/ICSI: a systematic review and meta-analysis.
This finding among the 11 findings on its endpoint

coenzyme Q10

Clinical pregnancy rate

raises

Effect as reported

1.84odds ratio

CI 1.33 to 2.53

Who
Women with diminished ovarian reserve undergoing IVF or ICSI; six randomised trials pooled. Five trials gave CoQ10 with DHEA, vitamin E or femoston against the same agent alone; one trial gave CoQ10 alone against no treatment
Dose studied
CoQ10 pretreatment for 60 days (alone) or three months (with DHEA, vitamin E or femoston) before ovarian stimulation; dose not stated in the text supplied

Moderate evidencePMID 39129455 · 2024

02 · The study

Study
meta-analysis
Duration
not reported

Evidence, by strength

  • strong
  • moderatethis finding
  • limited
  • very limited
  • insufficient

03 · The paper

Annals of medicine
What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6Y3PRB3M7FMS3AVV24BGWTX