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Catalyst

NMN zwitterionFinding

NMN zwitterion has no detected effect on maximal oxygen uptake

no difference foundModerate evidenceFinding

01 · The sentence it was drawn from

“No significant changes in HRmax, RERmax, HRR, O2-pulse, peak power, peak workload, ∆O2/∆WR, or VO2max were shown between the control and any of the NMN treatment groups.”
Quoted verbatim from Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study.
This finding among the 22 findings on its endpoint

NMN zwitterion

Maximal oxygen uptake

no difference found

Who
Healthy recreationally trained amateur runners aged 27-50 years, all arms in a 6-week aerobic training programme; three NMN dose groups (300, 600 and 1200 mg/day) compared with a placebo group, pooled statement across the dose groups
Dose studied
NMN powder 150, 300 or 600 mg twice daily (300, 600, 1200 mg/day) vs matching placebo powder (cranberry powder and maltodextrin), taken before training

Moderate evidencePMID 34238308 · 2021

02 · The study

Study
RCT
Duration
6 weeks

Evidence, by strength

  • strong
  • moderatethis finding
  • limited
  • very limited
  • insufficient

03 · The paper

Journal of the International Society of Sports Nutrition
What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6XH4TYESJFTAC7CPXKXCNRT