Zn(2+)/Finding
One finding, on its own
A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Decreases depressive symptom severity (across unharmonised instruments)
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“The meta-analysis of RCTs indicated that zinc supplementation significantly lowered depressive symptom scores of depressed patients [weighted mean difference (WMD = -4.15 point; 95% CI: -6.56, -1.75 point; P < 0.01)], and the improvement in depression status occurred only when zinc supplementation was prescribed as a monotherapy.”
Quoted verbatim from Zinc in depression: From development to treatment: A comparative/ dose response meta-analysis of observational studies and randomized controlled trials.. - Study
- meta-analysis
- Population
- Patients with depression; pooled RCTs, improvement reported only in trials giving zinc as monotherapy
Effect -4.15 mean difference, 95% CI -6.56 to -1.75
Zinc in depression: From development to treatment: A comparative/ dose response meta-analysis of observational studies and randomized controlled trials.2022PMID:32829928Permalink
Keep reading
- Everything the graph holds on Zn(2+)
- Every compound studied against Depressive symptom severity (across unharmonised instruments)
- How to read the evidence strength and the marks
To cite this finding: https://catalystproject.ai/e/01M5SBPZXPV8QF2H1KBZ386QTX