quercetin/Finding
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A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Inhibits SLCO1B1
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Finding“Quercetin competitively inhibited OATP1B1-mediated E3S uptake with a K(i) value of 17.9 ± 4.6 µm and also inhibited OATP1B1-mediated pravastatin uptake in a concentration dependent manner (IC(50) , 15.9 ± 1.4 µm).”
Quoted verbatim from Inhibition of the organic anion-transporting polypeptide 1B1 by quercetin: an in vitro and in vivo assessment.. - Study
- in vitro · not in humans
- Population
- HEK293 cells stably expressing OATP1B1; estrone-3-sulphate and pravastatin uptake
Inhibition of the organic anion-transporting polypeptide 1B1 by quercetin: an in vitro and in vivo assessment.2012PMID:22114872Permalink
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To cite this finding: https://catalystproject.ai/e/01M5RZG6NZJBHR17P0N2A14121