1,3,7,9-tetramethyluric acid/Finding
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Increases cortisol concentration
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“Repeated measures ANOVA results indicated greater salivary cortisol concentration in the theacrine conditions versus the placebo condition at 120 and 180 min post-treatment.”
Quoted verbatim from Assessing the impact of high theacrine doses on hemodynamic measures, cognitive performance, and physiological stress.. - Study
- crossover
- Dose
- single doses of 3, 6 or 9 mg/kg theacrine, 7-day washout between visits
- Population
- 19 healthy habitual caffeine consumers (5 men, 14 women); theacrine at 3, 6 and 9 mg/kg pooled as 'theacrine conditions' versus placebo; difference reported at the 120 and 180 min timepoints only
Assessing the impact of high theacrine doses on hemodynamic measures, cognitive performance, and physiological stress.2026PMID:41950524Permalink
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To cite this finding: https://catalystproject.ai/e/01M5RXE5PKPHEGXJ6M2QB1W869