quetiapine/Finding
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A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Increases antidepressant treatment response rate
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“The overall response rate, defined as ≥50% reduction on the depression rating scale scores, was higher in the quetiapine group at the end of the studies (RR 1.31, 95% CI 1.23 to 1.40; number needed to treat [NNT] 6, 95% CI 5 to 8).”
Quoted verbatim from Quetiapine for acute bipolar depression: a systematic review and meta-analysis.. - Study
- meta-analysis
- Dose
- 150-600 mg/day
- Population
- Adults and children/adolescents with acute bipolar I or II depression; pooled RCTs of quetiapine versus placebo, end of studies
Effect 1.31 risk ratio, 95% CI 1.23 to 1.4
Quetiapine for acute bipolar depression: a systematic review and meta-analysis.2014PMID:25028535Permalink
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To cite this finding: https://catalystproject.ai/e/01M45ADDX48T3Q8P3SYNNYY9EJ