curcumin/Finding
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A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Inhibits TRAF6
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Finding“As shown in, curcumin inhibited TRAF6 protein expression in OCPs in a concentration-dependent manner in the presence of RANKL.”
Quoted verbatim from Curcumin suppresses RANKL-induced osteoclast precursor autophagy in osteoclastogenesis by inhibiting RANK signaling and downstream JNK-BCL2-Beclin1 pathway.. - Study
- in vitro · not in humans
- Dose
- 0, 5, 10 or 15 μM
- Population
- mouse bone marrow-derived osteoclast precursors (OCPs) cultured with M-CSF and RANKL; western blot
Curcumin suppresses RANKL-induced osteoclast precursor autophagy in osteoclastogenesis by inhibiting RANK signaling and downstream JNK-BCL2-Beclin1 pathway.2024PMID:37179010Permalink
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To cite this finding: https://catalystproject.ai/e/01M4527BMWF42D98QBTGPN70NW