fucoxanthin/Finding
One finding, on its own
A single claim from the graph, with the grade computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Inhibits TLR4
PreliminaryGrade D, Preliminary. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“The expression of TLR4 and its downstream proteins myeloid differentiation factor 88 (MyD88), p-IκBα, and p-NF-κBp65 was significantly upregulated in the FFA group, and was significantly inhibited by treatment with fucoxanthin.”
Quoted verbatim from Fucoxanthin Attenuates Free Fatty Acid-Induced Nonalcoholic Fatty Liver Disease by Regulating Lipid Metabolism/Oxidative Stress/Inflammation via the AMPK/Nrf2/TLR4 Signaling Pathway.. - Study
- in vitro · not in humans
- Population
- Human Chang liver cell line, FFA-induced NAFLD cell model, fucoxanthin group
Fucoxanthin Attenuates Free Fatty Acid-Induced Nonalcoholic Fatty Liver Disease by Regulating Lipid Metabolism/Oxidative Stress/Inflammation via the AMPK/Nrf2/TLR4 Signaling Pathway.2022PMID:35447899Permalink
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To cite this finding: https://catalystproject.ai/e/01M3PA4XQDZ34Q7XY1CZCPJA97