caffeine/Finding
One finding, on its own
A single claim from the graph, with the grade computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Decreases tumour necrosis factor alpha concentration
LikelyGrade B, Likely. Human evidence with one recorded weakness, or capped at B by its design or by unread numbers.Finding“TNF-α at 38 weeks was 23% lower in the caffeine group compared to placebo, adjusting for baseline and covariates (P < 0.02, Table 3).”
Quoted verbatim from Intermittent hypoxia and caffeine in infants born preterm: the ICAF Randomized Clinical Trial.. - Study
- RCT
- Dose
- caffeine base 5 mg/kg/day once daily, escalating to 5 mg/kg twice daily at 36 weeks PMA, continued through 42 weeks 6 days PMA
- Population
- very preterm infants (<=30 weeks + 6 days gestational age) randomised to extended caffeine therapy through 42 weeks 6 days PMA vs placebo; secondary endpoint
Intermittent hypoxia and caffeine in infants born preterm: the ICAF Randomized Clinical Trial.2026PMID:41285561Permalink
Keep reading
- Everything the graph holds on caffeine
- Every compound studied against Tumour necrosis factor alpha concentration
- How to read the grade and the marks
To cite this finding: https://catalystproject.ai/e/01M3P35025S6MM09K7GCFVTC0D