L-citrulline/Finding
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A single claim from the graph, with the grade computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Binds JAK2
SpeculativeGrade F, Speculative. Mechanistic inference, no evidence found, or evidence weakened below D.Hypothesis“Reciprocally, increased citrulline directly binds to JAK2 and inhibits JAK2-STAT1 signaling.”
Quoted verbatim from Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses.. - Study
- mechanistic · not in humans
- Population
- macrophages
Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses.2022PMID:35016033Permalink
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To cite this finding: https://catalystproject.ai/e/01M3J8VF3XRZW1EN2JXBH937CS