lutein/Finding
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Inhibits FN1
SpeculativeGrade F, Speculative. Mechanistic inference, no evidence found, or evidence weakened below D.Finding“LU inhibited ACTA2, COL1A1, FN1, and CTGF mRNA expression and suppressed α-SMA, and FN1 protein expression induced by TGF-β1.”
Quoted verbatim from Lutein targeting orbital fibroblasts attenuates fibrotic and inflammatory effects in thyroid-associated ophthalmopathy.. - Study
- in vitro · not in humans
- Population
- orbital fibroblasts from patients with thyroid-associated ophthalmopathy, treated with TGF-β1 to induce fibrosis
Lutein targeting orbital fibroblasts attenuates fibrotic and inflammatory effects in thyroid-associated ophthalmopathy.2023PMID:37207866Permalink
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To cite this finding: https://catalystproject.ai/e/01M3J8H2BHBY60W622ZXHW50YT