creatine/Finding
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Is transported by SLC6A8
SpeculativeGrade F, Speculative. Mechanistic inference, no evidence found, or evidence weakened below D.Hypothesis“Creatine is transported into cells by the human creatine transporter (hCRT) (SLC6A8), an Na+/Cl--dependent symporter encoded on the X chromosome.”
Quoted verbatim from Structural insights into the substrate uptake and inhibition of the human creatine transporter (hCRT).. - Study
- mechanistic · not in humans
- Population
- purified recombinant human creatine transporter (hCRT/SLC6A8), cryo-EM structural study (apo, creatine-bound, RGX202-bound)
Structural insights into the substrate uptake and inhibition of the human creatine transporter (hCRT).2025PMID:40892912Permalink
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To cite this finding: https://catalystproject.ai/e/01M3J88R1681NHERMQCVWV062V