5-hydroxy-L-tryptophan/Finding
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Increases plasma/serum 5-hydroxytryptophan concentration
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×1“Administration of 5-HTP significantly increased plasma 5-HTP levels (p < 0.001), did not affect 5-HT levels (p > 0.05), while levels of the main metabolite of 5-HT, 5-hydroxyindoleacetic acid, increased significantly (p < 0.05) in both groups.”
Quoted verbatim from Visceral hypersensitivity in irritable bowel syndrome: evidence for involvement of serotonin metabolism--a preliminary study.. - Study
- RCT
- Dose
- 100 mg, single oral dose
- Population
- 15 IBS patients and 15 healthy volunteers; single 100 mg oral dose of 5-HTP vs placebo
Visceral hypersensitivity in irritable bowel syndrome: evidence for involvement of serotonin metabolism--a preliminary study.2016PMID:26031193Permalink
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To cite this finding: https://catalystproject.ai/e/01M30A1JD1RRFRACFKDEXEEFQX