coenzyme Q10/Finding
One finding, on its own
A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
No detected effect on total antioxidant capacity
LimitedEvidence strength: limited. Human evidence with several recorded weaknesses, or a design that tops out at limited.FindingNull resultreplicated ×2“There was no statistically significant change in TAC between the patients treated with doxorubicin + CoQ10 and doxorubicin + placebo.”
Quoted verbatim from Phase I Randomized, Placebo-Controlled, Cross-Over Dose-Finding Study of Coenzyme Q10 on Doxorubicin Pharmacokinetics during Breast Cancer Treatment.. - Study
- crossover
- Participants
- 6
- Dose
- 300 mg/day, two 150 mg softgel capsules once daily with food
- Population
- Women aged 21 or older with stage I-III breast cancer receiving dose-dense doxorubicin plus cyclophosphamide, each acting as her own control across one cycle with coenzyme Q10 and one with placebo; secondary endpoint.
Phase I Randomized, Placebo-Controlled, Cross-Over Dose-Finding Study of Coenzyme Q10 on Doxorubicin Pharmacokinetics during Breast Cancer Treatment.2025PMID:41261512Permalink
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To cite this finding: https://catalystproject.ai/e/01M10CXMZK1NWV2PBSYP64CK93