toxic epidermal necrolysis
MONDO:0019810Mondo
Findings
No curated finding names toxic epidermal necrolysis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Toxic epidermal necrolysis (TEN) is an acute and severe skin disease with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes.
Definition from the Mondo Disease Ontology (MONDO:0019810), read 2026-09-29. CC BY 4.0.
Features
64 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal blistering of the skinHPOHP:0008066
- Very frequent (80% to 99% of cases)
- Conjunctival hyperemiaHPOHP:0030953
- Very frequent (80% to 99% of cases)
- FatigueHPOHP:0012378
- Very frequent (80% to 99% of cases)
- FeverHPOHP:0001945
- Very frequent (80% to 99% of cases)
- Inflammatory abnormality of the skinHPOHP:0011123
- Very frequent (80% to 99% of cases)
- Abnormal bronchus morphologyHPOHP:0025426
- Frequent (30% to 79% of cases)
- Abnormality of the pharynxHPOHP:0000600
- Frequent (30% to 79% of cases)
- AcantholysisHPOHP:0100792
- Frequent (30% to 79% of cases)
- AnemiaHPOHP:0001903
- Frequent (30% to 79% of cases)
- AnorexiaHPOHP:0002039
- Frequent (30% to 79% of cases)
- AnxietyHPOHP:0000739
- Frequent (30% to 79% of cases)
- Atypical scarring of skinHPOHP:0000987
- Frequent (30% to 79% of cases)
Show the remaining 52
- ConjunctivitisHPOHP:0000509
- Frequent (30% to 79% of cases)
- CoughHPOHP:0012735
- Frequent (30% to 79% of cases)
- Elevated circulating hepatic transaminase concentrationHPOHP:0002910
- Frequent (30% to 79% of cases)
- Genital blisteringHPOHP:0031464
- Frequent (30% to 79% of cases)
- HeadacheHPOHP:0002315
- Frequent (30% to 79% of cases)
- Hyperpigmentation of the skinHPOHP:0000953
- Frequent (30% to 79% of cases)
Where it sits
- A kind of
Other names
3 names
Resolves to: toxic epidermal necrolysis
- Also called
- SJS-TENTENtoxic epidermolysis