tooth agenesis, selective, 8
Findings
No curated finding names tooth agenesis, selective, 8 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any tooth agenesis in which the cause of the disease is a mutation in the WNT10B gene.
Definition from the Mondo Disease Ontology (MONDO:0014901), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
HPO, annotations 2026-09-02
Features
5 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- MicrodontiaHPOHP:0000691
- 3 of 3 reported patients
- Selective tooth agenesisHPOHP:0001592
- 3 of 3 reported patients
- Sparse eyebrowHPOHP:0045075
- 3 of 3 reported patients
- Dry skinHPOHP:0000958
- 2 of 3 reported patients
- Sparse hairHPOHP:0008070
- 2 of 3 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- WNT10BHGNC:12775
- Strong · PanelApp Australia · Autosomal dominant · 2025
- Moderate · Ambry Genetics · Autosomal dominant · 2018
- Limited · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2021
Where it sits
- A kind of
Other names
5 names
Resolves to: tooth agenesis, selective, 8
- Also called
- STHAG8tooth agenesis caused by mutation in WNT10Btooth agenesis, selective, 8; STHAG8tooth agenesis, selective, type 8WNT10B tooth agenesis