tooth agenesis, selective, 7
MONDO:0014749Mondo
Findings
No curated finding names tooth agenesis, selective, 7 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any tooth agenesis in which the cause of the disease is a mutation in the LRP6 gene.
Definition from the Mondo Disease Ontology (MONDO:0014749), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
HPO, annotations 2026-09-02
Features
2 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Agenesis of permanent teethHPOHP:0006349
- 20 of 26 reported patients
- TaurodontiaHPOHP:0000679
- 6 of 28 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- LRP6HGNC:6698
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2022
- Strong · PanelApp Australia · Autosomal dominant · 2025
- Limited · G2P · Autosomal dominant · 2017
Where it sits
- A kind of
Other names
5 names
Resolves to: tooth agenesis, selective, 7
- Also called
- LRP6 tooth agenesisSTHAG7tooth agenesis caused by mutation in LRP6tooth agenesis, selective, 7; STHAG7tooth agenesis, selective, type 7