tooth agenesis, selective, 4
Findings
No curated finding names tooth agenesis, selective, 4 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any tooth agenesis in which the cause of the disease is a mutation in the WNT10A gene.
Definition from the Mondo Disease Ontology (MONDO:0007881), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance · Autosomal recessive inheritance
HPO, annotations 2026-09-02
Features
14 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Agenesis of permanent teethHPOHP:0006349
- 12 of 12 reported patients
- Dystrophic toenailHPOHP:0001810
- 8 of 12 reported patients
- Sparse body hairHPOHP:0002231
- 6 of 9 reported patients
- Dry skinHPOHP:0000958
- 7 of 11 reported patients
- Sparse eyebrowHPOHP:0045075
- 7 of 11 reported patients
- Sparse scalp hairHPOHP:0002209
- 7 of 12 reported patients
- Abnormal primary tooth morphologyHPOHP:0006481
Show the remaining 2
- PhotophobiaHPOHP:0000613
- 3 of 11 reported patients
- Thin skinHPOHP:0000963
- 3 of 11 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- WNT10AHGNC:13829
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2023
Where it sits
Other names
3 names
Resolves to: tooth agenesis, selective, 4
- Also called
- tooth agenesis caused by mutation in WNT10Atooth agenesis, selective, type 4WNT10A tooth agenesis