sporadic pheochromocytoma/secreting paraganglioma
Findings
No curated finding names sporadic pheochromocytoma/secreting paraganglioma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Sporadic pheochromocytoma/secreting paraganglioma are isolated, non-familial, catecholamin-producing tumors arising from neuroendocrine chromaffin cells in the adrenal medulla or in extra-adrenal chromaffin tissue, respectively. The majority of these tumors are benign and the presenting symptoms are typically caused by the increased catecholamine production of the tumor, including hypertension (often paroxysmal), tachycardia, anxiety and/or excessive sweating.
Definition from the Mondo Disease Ontology (MONDO:0017190), read 2026-09-29. CC BY 4.0.
Features
46 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Adrenal pheochromocytomaHPOHP:0006748
- Very frequent (80% to 99% of cases)
- Extraadrenal pheochromocytomaHPOHP:0006737
- Very frequent (80% to 99% of cases)
- ParagangliomaHPOHP:0002668
- Very frequent (80% to 99% of cases)
- Cerebral hemorrhageHPOHP:0001342
- Frequent (30% to 79% of cases)
- Chest painHPOHP:0100749
- Frequent (30% to 79% of cases)
- DysphoniaHPOHP:0001618
- Frequent (30% to 79% of cases)
- Elevated urinary dopamine level
Show the remaining 34
- FatigueHPOHP:0012378
- Frequent (30% to 79% of cases)
- FlushingHPOHP:0031284
- Frequent (30% to 79% of cases)
- Glomerular sclerosisHPOHP:0000096
- Frequent (30% to 79% of cases)
- HypercalcemiaHPOHP:0003072
- Frequent (30% to 79% of cases)
- HypertensionHPOHP:0000822
- Frequent (30% to 79% of cases)
- Hypertension associated with pheochromocytomaHPOHP:0002640
- Frequent (30% to 79% of cases)
Where it sits
- A kind of