spermatogenic failure, X-linked, 9
MONDO:0976123Mondo
Findings
No curated finding names spermatogenic failure, X-linked, 9 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
- Inheritance
- X-linked inheritance
- Onset and course
- Young adult onset
HPO, annotations 2026-09-02
Features
10 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Decreased serum testosterone concentrationHPOHP:0040171
- 2 of 2 reported patients
- Decreased testicular sizeHPOHP:0008734
- 2 of 2 reported patients
- Elevated circulating follicle stimulating hormone levelHPOHP:0008232
- 2 of 2 reported patients
- Elevated circulating luteinizing hormone levelHPOHP:0011969
- 2 of 2 reported patients
- Leydig cell neoplasiaHPOHP:0100618
- 1 of 1 reported patient
- Male infertilityHPOHP:0003251
- 2 of 2 reported patients
- Non-obstructive azoospermiaHPOHP:0011961
- 2 of 2 reported patients
- Spermatogenesis maturation arrestHPOHP:0031038
- 2 of 2 reported patients
- LymphadenopathyHPOHP:0002716
- 0 of 2 reported patients
- NeoplasmHPOHP:0002664
- 0 of 1 reported patient
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- RBBP7HGNC:9890
- Limited · Ambry Genetics · X-linked · 2025
Where it sits
- A kind of