secondary syringomyelia
Findings
No curated finding names secondary syringomyelia yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Secondary syringomyelia is a rare medullar disease defined as a development of a fluid-filled cavity or syrinx within the spinal cord due to blockage of CSF circulation (e.g., due to basal archnoiditis, meningeal carcinomatosis, various mass lesions), spinal cord injury (e.g., due to trauma, radiation necrosis, hemorrhage, spinal abscess), spinal dysraphism or intramedullary tumors. It presents with neuropathic pain, numbness, muscular weakness, changes in tone or spasticity or autonomic changes (hyperhidrosis, heart rate or blood pressure instability). Selective loss of pain and temperature with relative preservation of dorsal column function (touch and pressure) are classic findings.
Definition from the Mondo Disease Ontology (MONDO:0020509), read 2026-09-29. CC BY 4.0.
Features
26 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- SyringomyeliaHPOHP:0003396
- Obligate (100% of cases)
- Hyperintensity of MRI T2 signal of the spinal cordHPOHP:0040272
- Very frequent (80% to 99% of cases)
- Back painHPOHP:0003418
- Frequent (30% to 79% of cases)
- Cranial nerve paralysisHPOHP:0006824
- Frequent (30% to 79% of cases)
- CSF pleocytosisHPOHP:0012229
- Frequent (30% to 79% of cases)
- DysphoniaHPOHP:0001618
- Frequent (30% to 79% of cases)
- Facial paralysis
Show the remaining 14
- ParesthesiaHPOHP:0003401
- Frequent (30% to 79% of cases)
- Paroxysmal vertigoHPOHP:0010532
- Frequent (30% to 79% of cases)
- Sensory ataxiaHPOHP:0010871
- Frequent (30% to 79% of cases)
- Somatic sensory dysfunctionHPOHP:0003474
- Frequent (30% to 79% of cases)
- Blurred visionHPOHP:0000622
- Occasional (5% to 29% of cases)
- Bulbar palsyHPOHP:0001283
- Occasional (5% to 29% of cases)
Where it sits
- A kind of