pediatric systemic lupus erythematosus
MONDO:0019725Mondo
Findings
No curated finding names pediatric systemic lupus erythematosus yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Features
53 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Decreased circulating complement C3 concentrationHPOHP:0005421
- Very frequent (80% to 99% of cases)
- Decreased circulating complement C4 concentrationHPOHP:0045042
- Very frequent (80% to 99% of cases)
- Elevated erythrocyte sedimentation rateHPOHP:0003565
- Very frequent (80% to 99% of cases)
- Abnormality of the gastrointestinal tractHPOHP:0011024
- Frequent (30% to 79% of cases)
- Abnormality of the skinHPOHP:0000951
- Frequent (30% to 79% of cases)
- Abnormality of the urinary systemHPOHP:0000079
- Frequent (30% to 79% of cases)
- Antinuclear antibody positivityHPOHP:0003493
- Frequent (30% to 79% of cases)
- Antiphospholipid antibody positivityHPOHP:0003613
- Frequent (30% to 79% of cases)
- Decreased total leukocyte countHPOHP:0001882
- Frequent (30% to 79% of cases)
- Decreased total lymphocyte countHPOHP:0001888
- Frequent (30% to 79% of cases)
- EdemaHPOHP:0000969
- Frequent (30% to 79% of cases)
- FeverHPOHP:0001945
- Frequent (30% to 79% of cases)
Show the remaining 41
- HematuriaHPOHP:0000790
- Frequent (30% to 79% of cases)
- Increased circulating lactate dehydrogenase concentrationHPOHP:0025435
- Frequent (30% to 79% of cases)
- LymphadenopathyHPOHP:0002716
- Frequent (30% to 79% of cases)
- Microangiopathic hemolytic anemiaHPOHP:0001937
- Frequent (30% to 79% of cases)
- NephritisHPOHP:0000123
- Frequent (30% to 79% of cases)
- Nephrotic syndromeHPOHP:0000100
- Frequent (30% to 79% of cases)
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- SAT1HGNC:10540
- Limited · ClinGen · X-linked · 2024
Where it sits
- A kind of
Other names
2 names
Resolves to: pediatric systemic lupus erythematosus
- Also called
- SLE, paediatric onsetSLE, pediatric onset