Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development
MONDO:0957576Mondo
Findings
No curated finding names Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
- Inheritance
- Autosomal recessive inheritance
- Onset and course
- Juvenile onset
HPO, annotations 2026-09-02
Features
10 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Intellectual disabilityHPOHP:0001249
- 4 of 4 reported patients
- Parkinsonism with favorable response to dopaminergic medicationHPOHP:0002548
- 4 of 4 reported patients
- BradykinesiaHPOHP:0002067
- 3 of 4 reported patients
- Resting tremorHPOHP:0002322
- 2 of 4 reported patients
- AnxietyHPOHP:0000739
- 1 of 4 reported patients
- DepressionHPOHP:0000716
- 1 of 4 reported patients
- DisinhibitionHPOHP:0000734
- 1 of 4 reported patients
- DroolingHPOHP:0002307
- 1 of 4 reported patients
- Restless legsHPOHP:0012452
- 1 of 4 reported patients
- RigidityHPOHP:0002063
- 1 of 4 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- PTPAHGNC:9308
- Moderate · PanelApp Australia · Autosomal recessive · 2025
Where it sits
- A kind of