palmoplantar pustulosis
Findings
No curated finding names palmoplantar pustulosis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A rare skin disease characterized by chronic eruption of sterile pustules on an erythematous and desquamative background, affecting the palms and soles, sometimes also the lateral aspects of hands and feet. The lesions are usually painful. Nail lesions (such as nail pitting, onycholysis, subungual pustules, and nail dystrophy) are also observed. The condition takes a chronic and relapsing course. Typical associations are psoriatic arthritis, thyroid gland dysfunction, and smoking.
Definition from the Mondo Disease Ontology (MONDO:0015597), read 2026-09-29. CC BY 4.0.
Genes
2 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
Where it sits
- A kind of
Other names
6 names
Resolves to: palmoplantar pustulosis
- Also called
- localised pustular psoriasislocalized pustular psoriasisLPPPPPpustulosis of palm and solepustulosis palmaris et plantaris