osteoporosis
Findings
No curated finding names osteoporosis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A condition of reduced bone mass, with decreased cortical thickness and a decrease in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. Osteoporosis is classified as primary (Type 1, postmenopausal osteoporosis; Type 2, age-associated osteoporosis; and idiopathic, which can affect juveniles, premenopausal women, and middle-aged men) and secondary osteoporosis (which results from an identifiable cause of bone mass loss).
Definition from the Mondo Disease Ontology (MONDO:0005298), read 2026-09-29. CC BY 4.0.
Genes
2 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
Where it sits
Other names
3 names
Resolves to: osteoporosis
- Also called
- bone mineral density quantitative trait locusosteoporosis, involutionalosteoporosis, postmenopausal