orofacial cleft 11
MONDO:0010906Mondo
Findings
No curated finding names orofacial cleft 11 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any orofacial cleft in which the cause of the disease is a mutation in the BMP4 gene.
Definition from the Mondo Disease Ontology (MONDO:0010906), read 2026-09-29. CC BY 4.0.
- Inheritance
- Polygenic inheritance
HPO, annotations 2026-09-02
Features
2 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Cleft lipHPOHP:0410030
- Cleft palateHPOHP:0000175
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- BMP4HGNC:1071
- Strong · PanelApp Australia · Autosomal dominant · 2025
- Limited · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2020
Where it sits
- A kind of
Other names
3 names
Resolves to: orofacial cleft 11
- Also called
- BMP4 orofacial cleftorofacial cleft caused by mutation in BMP4orofacial cleft type 11