MHC class II deficiency

Findings

No curated finding names MHC class II deficiency yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.

Definition

What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.

Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.

Where it sits

A kind of

• familial severe combined immunodeficiency

Narrower terms (5)

• MHC class II deficiency 1
• MHC class II deficiency 2
• MHC class II deficiency 3
• MHC class II deficiency 4
• MHC class II deficiency 5

Resolves to: MHC class II deficiency

Also called

HLA class 2-negative SCIDHLA class 2-negative severe combined immunodeficiencyimmunodeficiency by defective expression of HLA class type 2major histocompatibility complex class II expression deficiencyMHC class II expression deficiency