limited cutaneous systemic sclerosis
MONDO:0016358Mondo
Findings
No curated finding names limited cutaneous systemic sclerosis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Limited cutaneous systemic sclerosis (lcSSc) is a subtype of systemic sclerosis (SSc) characterized by the association of Raynaud's phenomenon with skin fibrosis limited to the hands, face, feet and forearms.
Definition from the Mondo Disease Ontology (MONDO:0016358), read 2026-09-29. CC BY 4.0.
Features
15 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal skin pigmentationHPOHP:0001000
- Very frequent (80% to 99% of cases)
- Abnormality of the skinHPOHP:0000951
- Very frequent (80% to 99% of cases)
- AutoimmunityHPOHP:0002960
- Very frequent (80% to 99% of cases)
- Hypopigmented skin patchesHPOHP:0001053
- Very frequent (80% to 99% of cases)
- Narrow foramen obturatoriumHPOHP:0100958
- Very frequent (80% to 99% of cases)
- DysphagiaHPOHP:0002015
- Frequent (30% to 79% of cases)
- Gastroesophageal refluxHPOHP:0002020
- Frequent (30% to 79% of cases)
- Mucosal telangiectasiaeHPOHP:0100579
- Frequent (30% to 79% of cases)
- Nausea and vomitingHPOHP:0002017
- Frequent (30% to 79% of cases)
- Skin ulcerHPOHP:0200042
- Frequent (30% to 79% of cases)
- Telangiectasia of the skinHPOHP:0100585
- Frequent (30% to 79% of cases)
- Foot joint contractureHPOHP:0008366
- Occasional (5% to 29% of cases)
Show the remaining 3
- Joint contracture of the handHPOHP:0009473
- Occasional (5% to 29% of cases)
- Pulmonary arterial hypertensionHPOHP:0002092
- Occasional (5% to 29% of cases)
- Pulmonary fibrosisHPOHP:0002206
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
- Narrower terms (1)
Other names
2 names
Resolves to: limited cutaneous systemic sclerosis
- Also called
- limited cutaneous systemic sclerodermalimited scleroderma