leukemia, acute lymphoblastic, susceptibility to, 3
MONDO:0014241Mondo
Findings
No curated finding names leukemia, acute lymphoblastic, susceptibility to, 3 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any precursor B-cell acute lymphoblastic leukemia in which the cause of the disease is a mutation in the PAX5 gene.
Definition from the Mondo Disease Ontology (MONDO:0014241), read 2026-09-29. CC BY 4.0.
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- PAX5HGNC:8619
- Definitive · ClinGen · Autosomal dominant · 2025
- Moderate · Ambry Genetics · Autosomal dominant · 2024
- Limited · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2021
Where it sits
- A kind of
Other names
6 names
Resolves to: leukemia, acute lymphoblastic, susceptibility to, 3
- Also called
- leukemia, acute lymphoblastic, susceptibility to, type 3PAX5 precursor B-cell acute lymphoblastic leukaemiaPAX5 precursor B-cell acute lymphoblastic leukemiaPAX5-related leukemia predispositionprecursor B-cell acute lymphoblastic leukaemia caused by mutation in PAX5precursor B-cell acute lymphoblastic leukemia caused by mutation in PAX5