juvenile myelomonocytic leukemia
Findings
No curated finding names juvenile myelomonocytic leukemia yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A myelodysplastic/myeloproliferative neoplasm of childhood that is characterized by proliferation principally of the granulocytic and monocytic lineages. Myelomonocytic proliferation is seen in the bone marrow and the blood. The leukemic cells may infiltrate any tissue, however liver, spleen, lymph nodes, skin, and respiratory tract are the most common sites of involvement. (WHO, 2001)
Definition from the Mondo Disease Ontology (MONDO:0011908), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
HPO, annotations 2026-09-02
Features
1 feature
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Juvenile myelomonocytic leukemiaHPOHP:0012209
- Infantile onset
Genes
2 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
Where it sits
- A kind of
Other names
11 names
Resolves to: juvenile myelomonocytic leukemia
- Also called
- JCMLJMMLjuvenile chronic myelogenous leukaemiajuvenile chronic myelogenous leukemiajuvenile chronic myeloid leukaemiajuvenile chronic myeloid leukemiajuvenile chronic myelomonocytic leukaemiajuvenile chronic myelomonocytic leukemiajuvenile myelomonocytic leukemia, autosomal dominant, somatic mutationleukemia, juvenile myelomonocytic, autosomal dominant, somatic mutationleukemia, juvenile myelomonocytic, somatic