intellectual disability, X-linked 101
Findings
No curated finding names intellectual disability, X-linked 101 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any non-syndromic X-linked intellectual disability in which the cause of the disease is a mutation in the MID2 gene.
Definition from the Mondo Disease Ontology (MONDO:0010489), read 2026-09-29. CC BY 4.0.
- Inheritance
- X-linked recessive inheritance
- Onset and course
- Infantile onset
HPO, annotations 2026-09-02
Features
12 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Global developmental delayHPOHP:0001263
- 6 of 6 reported patients
- HyperactivityHPOHP:0000752
- 6 of 6 reported patients
- Intellectual disabilityHPOHP:0001249
- 6 of 6 reported patients
- Long faceHPOHP:0000276
- 4 of 6 reported patients
- Poor speechHPOHP:0002465
- 4 of 6 reported patients
- StrabismusHPOHP:0000486
- 4 of 6 reported patients
- SeizureHPOHP:0001250
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- MID2HGNC:7096
- Limited · Labcorp Genetics (formerly Invitae) · Unknown · 2021
Where it sits
Other names
5 names
Resolves to: intellectual disability, X-linked 101
- Also called
- intellectual developmental disorder, X-linked 101, X-linked recessiveintellectual disability, X-linked type 101mental retardation, X-linked type 101MID2 non-syndromic X-linked intellectual disabilitynon-syndromic X-linked intellectual disability caused by mutation in MID2