hypotrichosis 8
MONDO:0010206Mondo
Findings
No curated finding names hypotrichosis 8 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any hypotrichosis in which the cause of the disease is a mutation in the LPAR6 gene.
Definition from the Mondo Disease Ontology (MONDO:0010206), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal recessive inheritance
- Onset and course
- Congenital onset
HPO, annotations 2026-09-02
Features
7 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Coarse hairHPOHP:0002208
- 14 of 14 reported patients
- Dry hairHPOHP:0011359
- 14 of 14 reported patients
- Sparse scalp hairHPOHP:0002209
- 14 of 14 reported patients
- Woolly hairHPOHP:0002224
- 14 of 14 reported patients
- Abnormality of the dentitionHPOHP:0000164
- 0 of 14 reported patients
- HyperhidrosisHPOHP:0000975
- 0 of 14 reported patients
- Sparse eyelashesHPOHP:0000653
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- LPAR6HGNC:15520
- Strong · Ambry Genetics · Autosomal recessive · 2018
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal recessive · 2020
- Strong · G2P · Autosomal recessive · 2025
Where it sits
Other names
6 names
Resolves to: hypotrichosis 8
- Also called
- hypotrichosis caused by mutation in LPAR6hypotrichosis type 8hypotrichosis, localized, autosomal recessive 3HYPT8LAH3LPAR6 hypotrichosis