hypertrophic cardiomyopathy 13
Findings
No curated finding names hypertrophic cardiomyopathy 13 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any hypertrophic cardiomyopathy in which the cause of the disease is a mutation in the TNNC1 gene.
Definition from the Mondo Disease Ontology (MONDO:0013195), read 2026-09-29. CC BY 4.0.
- Onset and course
- Middle age onset · Juvenile onset · Young adult onset
HPO, annotations 2026-09-02
Features
11 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Complete right bundle branch blockHPOHP:0011712
- 1 of 1 reported patient
- Concentric hypertrophic cardiomyopathyHPOHP:0005157
- 1 of 1 reported patient
- Exertional dyspneaHPOHP:0002875
- 1 of 1 reported patient
- Hypertrophic cardiomyopathyHPOHP:0001639
- 4 of 4 reported patients
- Left anterior fascicular blockHPOHP:0011711
- 1 of 1 reported patient
- Angina pectorisHPOHP:0001681
- 2 of 4 reported patients
- DyspneaHPO
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- TNNC1HGNC:11943
- Definitive · G2P · Autosomal dominant · 2025
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2021
- Strong · PanelApp Australia · Autosomal dominant · 2025
Where it sits
- A kind of
Other names
6 names
Resolves to: hypertrophic cardiomyopathy 13
- Also called
- cardiomyopathy, familial hypertrophic, type 13cardiomyopathy, hypertrophic, 13CMH13hypertrophic cardiomyopathy caused by mutation in TNNC1hypertrophic cardiomyopathy type 13TNNC1 hypertrophic cardiomyopathy