herpes simplex encephalitis, susceptibility to, 1
Findings
No curated finding names herpes simplex encephalitis, susceptibility to, 1 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A Mendelian susceptibility or predisposition to herpes simplex infection induced encephalitis in which the cause of the diseas is a mutation in the UNC93B1 gene.
Definition from the Mondo Disease Ontology (MONDO:0024563), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal recessive inheritance
HPO, annotations 2026-09-02
Features
2 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- HSV encephalitisHPOHP:0012302
- Recurrent herpesHPOHP:0005353
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- UNC93B1HGNC:13481
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal recessive · 2023
- Moderate · PanelApp Australia · Autosomal recessive · 2025
Where it sits
- A kind of
Other names
2 names
Resolves to: herpes simplex encephalitis, susceptibility to, 1
- Also called
- herpes simplex encephalitis caused by mutation in UNC93B1UNC93B1 herpes simplex encephalitis