hereditary spastic paraplegia 16
MONDO:0010287Mondo
Findings
No curated finding names hereditary spastic paraplegia 16 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A hereditary spastic paraplegia that has material basis in variation in the chromosome region Xq11.2.
Definition from the Mondo Disease Ontology (MONDO:0010287), read 2026-09-29. CC BY 4.0.
Features
9 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal hallux morphologyHPOHP:0001844
- Frequent (30% to 79% of cases)
- Expressive aphasiaHPOHP:0002427
- Frequent (30% to 79% of cases)
- Functional abnormality of the bladderHPOHP:0000009
- Frequent (30% to 79% of cases)
- Functional abnormality of the gastrointestinal tractHPOHP:0012719
- Frequent (30% to 79% of cases)
- Mild intellectual disabilityHPOHP:0001256
- Frequent (30% to 79% of cases)
- Motor delayHPOHP:0001270
- Frequent (30% to 79% of cases)
- NystagmusHPOHP:0000639
- Frequent (30% to 79% of cases)
- TetraplegiaHPOHP:0002445
- Frequent (30% to 79% of cases)
- Visual lossHPOHP:0000572
- Frequent (30% to 79% of cases)
Where it sits
- A kind of
Other names
4 names
Resolves to: hereditary spastic paraplegia 16
- Also called
- hereditary spastic paraplegia type 16spastic paraplegia 16, X-linked, complicated, X-linked recessiveSPG16X-linked spastic paraplegia type 16