hereditary spastic paraplegia 14
MONDO:0011522Mondo
Findings
No curated finding names hereditary spastic paraplegia 14 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A hereditary spastic paraplegia that has material basis in variation in the chromosome region 3q27-q28.
Definition from the Mondo Disease Ontology (MONDO:0011522), read 2026-09-29. CC BY 4.0.
Features
7 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Babinski signHPOHP:0003487
- Very frequent (80% to 99% of cases)
- HyperreflexiaHPOHP:0001347
- Very frequent (80% to 99% of cases)
- Lower limb hypertoniaHPOHP:0006895
- Very frequent (80% to 99% of cases)
- Mild intellectual disabilityHPOHP:0001256
- Very frequent (80% to 99% of cases)
- Motor axonal neuropathyHPOHP:0007002
- Very frequent (80% to 99% of cases)
- Pes cavusHPOHP:0001761
- Very frequent (80% to 99% of cases)
- Spastic gaitHPOHP:0002064
- Very frequent (80% to 99% of cases)
Where it sits
- A kind of
Other names
5 names
Resolves to: hereditary spastic paraplegia 14
- Also called
- autosomal recessive spastic paraplegia type 14hereditary spastic paraplegia type 14spastic paraplegia 14spastic paraplegia 14, autosomal recessiveSPG14