hereditary gingival fibromatosis
Findings
No curated finding names hereditary gingival fibromatosis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Hereditary gingival fibromatosis (HGF) is a rare benign, slowly progressive, non-inflammatory fibrous hyperplasia of the maxillary and mandibular gingivae that generally occurs with the eruption of the permanent (or more rarely the primary) dentition or even at birth. It presents as a localized or generalized, smooth or nodular overgrowth of the gingival tissues of varying severity. It can be isolated, with autosomal dominant inheritance, or as part of a syndrome.
Definition from the Mondo Disease Ontology (MONDO:0016070), read 2026-09-29. CC BY 4.0.
Features
2 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Gingival fibromatosisHPOHP:0000169
- Very frequent (80% to 99% of cases)
- Gingival overgrowthHPOHP:0000212
- Very frequent (80% to 99% of cases)
Genes
4 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
Where it sits
Other names
3 names
Resolves to: hereditary gingival fibromatosis
- Also called
- autosomal dominant gingival fibromatosisautosomal dominant gingival hyperplasiahereditary gingival hyperplasia