Felty syndrome
MONDO:0007603Mondo
Findings
No curated finding names Felty syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Felty syndrome (FS), also known as ''super rheumatoid'' disease, is a severe form of rheumatoid arthritis (RA), characterized by a triad of RA, splenomegaly and neutropenia, resulting in susceptibility to bacterial infections.
Definition from the Mondo Disease Ontology (MONDO:0007603), read 2026-09-29. CC BY 4.0.
Features
37 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal joint morphologyHPOHP:0001367
- Very frequent (80% to 99% of cases)
- ArthralgiaHPOHP:0002829
- Very frequent (80% to 99% of cases)
- ArthritisHPOHP:0001369
- Very frequent (80% to 99% of cases)
- AutoimmunityHPOHP:0002960
- Very frequent (80% to 99% of cases)
- Decreased total neutrophil countHPOHP:0001875
- Very frequent (80% to 99% of cases)
- ImmunodeficiencyHPOHP:0002721
- Very frequent (80% to 99% of cases)
- Limitation of joint mobilityHPOHP:0001376
- Very frequent (80% to 99% of cases)
- OsteolysisHPOHP:0002797
- Very frequent (80% to 99% of cases)
- Recurrent infectionsHPOHP:0002719
- Very frequent (80% to 99% of cases)
- Recurrent respiratory infectionsHPOHP:0002205
- Very frequent (80% to 99% of cases)
- Subcutaneous noduleHPOHP:0001482
- Very frequent (80% to 99% of cases)
- SynovitisHPOHP:0100769
- Very frequent (80% to 99% of cases)
Show the remaining 25
- Abnormal lymphocyte morphologyHPOHP:0004332
- Frequent (30% to 79% of cases)
- AnemiaHPOHP:0001903
- Frequent (30% to 79% of cases)
- Chronic otitis mediaHPOHP:0000389
- Frequent (30% to 79% of cases)
- LymphadenopathyHPOHP:0002716
- Frequent (30% to 79% of cases)
- Recurrent pharyngitisHPOHP:0100776
- Frequent (30% to 79% of cases)
- Recurrent pneumoniaHPOHP:0006532
- Frequent (30% to 79% of cases)
Where it sits
Other names
3 names
Resolves to: Felty syndrome
- Also called
- Felty's syndromerheumatoid arthritis with splenoadenomegaly and leukopeniasplenomegaly-neutropenia-rheumatoid arthritis syndrome