Duane syndrome type 1
Findings
No curated finding names Duane syndrome type 1 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Duane syndrome type 1 is the most common type of Duane syndrome, an eye movement disorder that is present at birth. People with Duane syndrome have restricted ability to move the affected eye(s) outward toward the ear (abduction) and/or inward toward the nose (adduction). The different types are distinguished by the eye movements that are most restricted. Duane syndrome type 1 is characterized by absent to very restricted abduction and normal to mildly restricted adduction. The eye opening (palpebral fissure) narrows and the eyeball retracts into the orbit with adduction. With abduction, the reverse occurs. One or both eyes may be affected. The majority of cases are sporadic (not inherited), while about 10% are familial. 70% of affected people do not have any other abnormalities at birth (isolated Duane syndrome). Treatment is mainly supportive and may include glasses or contact lenses for vision correction, eye patches, or surgery.
Definition from the Mondo Disease Ontology (MONDO:0024265), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
HPO, annotations 2026-09-02
Features
6 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Duane anomalyHPOHP:0009921
- Congenital onset
- EsotropiaHPOHP:0000565
- Impaired ocular abductionHPOHP:0000634
- Impaired ocular adductionHPOHP:0000542
- Palpebral fissure narrowing on adductionHPOHP:0000661
- StrabismusHPOHP:0000486
- Congenital onset
Where it sits
- A kind of
Other names
2 names
Resolves to: Duane syndrome type 1
- Also called
- Duane retraction syndrome 1DURS1