core binding factor acute myeloid leukemia
MONDO:0850269Mondo
Findings
No curated finding names core binding factor acute myeloid leukemia yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
An acute myeloid leukemia that is characterized by the presence of t(8;21)(q22;q22) or inv(16)(p13q22)/t(16;16)(p13;q22). These cytogenetic abnormalities result in disruption of the transcription factor CBF, which is a regulator of normal hematopoiesis.
Definition from the Mondo Disease Ontology (MONDO:0850269), read 2026-09-29. CC BY 4.0.
Where it sits
- A kind of