common variable immunodeficiency

Findings

No curated finding names common variable immunodeficiency yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.

What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, hp/releases/2026-09-01.

Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.

Where it sits

A kind of

• syndromic agammaglobulinemia

Narrower terms (16)

• combined immunodeficiency due to LRBA deficiency
• IL21-related infantile inflammatory bowel disease
• immune deficiency, familial variable
• immunodeficiency, common variable, 1
• immunodeficiency, common variable, 10
• immunodeficiency, common variable, 12
• immunodeficiency, common variable, 14
• immunodeficiency, common variable, 15
• immunodeficiency, common variable, 2
• immunodeficiency, common variable, 3
• immunodeficiency, common variable, 4
• immunodeficiency, common variable, 5
• immunodeficiency, common variable, 6
• immunodeficiency, common variable, 7
• immunodeficiency, common variable, due to APRIL deficiency
• pancytopenia due to IKZF1 mutations

Resolves to: common variable immunodeficiency

Also called

Common Variable Immune Deficiencyprimary antibody deficiencyprimary hypogammaglobulinemiasecondary hypogammaglobulinemia