colorectal cancer, susceptibility to, 12
MONDO:0014038Mondo
Findings
No curated finding names colorectal cancer, susceptibility to, 12 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any colorectal cancer in which the cause of the disease is a mutation in the POLE gene.
Definition from the Mondo Disease Ontology (MONDO:0014038), read 2026-09-29. CC BY 4.0.
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- POLEHGNC:9177
- Strong · Ambry Genetics · Autosomal dominant · 2023
- Strong · Genomics England PanelApp · Autosomal dominant · 2020
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2023
Where it sits
- A kind of
Other names
3 names
Resolves to: colorectal cancer, susceptibility to, 12
- Also called
- colorectal cancer caused by mutation in POLEcolorectal cancer, susceptibility to, type 12POLE colorectal cancer