chronic obstructive pulmonary disease
Findings
No curated finding names chronic obstructive pulmonary disease yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A chronic and progressive lung disorder characterized by the loss of elasticity of the bronchial tree and the air sacs, destruction of the air sacs wall, thickening of the bronchial wall, and mucous accumulation in the bronchial tree. The pathologic changes result in the disruption of the air flow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough, and chest tightness. The two main types of chronic obstructive pulmonary disease are chronic obstructive bronchitis and emphysema.
Definition from the Mondo Disease Ontology (MONDO:0005002), read 2026-09-29. CC BY 4.0.
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- HMOX1HGNC:5013
- Limited · Labcorp Genetics (formerly Invitae) · Unknown · 2020
Where it sits
Other names
12 names
Resolves to: chronic obstructive pulmonary disease
- Also called
- chronic obstructive airways diseasechronic obstructive lung diseasechronic obstructive pulmonary disease (COPD)chronic obstructive pulmonary disease, (COPD)COLDcold (chronic obstructive lung disease)COPDCOPD, chronic obstructive pulmonary diseasedisease (COPD), chronic obstructiveobstructive lung disease, chronicobstructive pulmonary disease (COPD), chronicpulmonary disease (COPD), chronic obstructive