chondrosarcoma
Findings
No curated finding names chondrosarcoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A malignant cartilaginous matrix-producing mesenchymal neoplasm arising from the bone and soft tissue. It usually affects middle-aged to elderly adults. The pelvic bones, ribs, shoulder girdle, and long bones are the most common sites of involvement. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion.
Definition from the Mondo Disease Ontology (MONDO:0008977), read 2026-09-29. CC BY 4.0.
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- EXT1HGNC:3512
- Strong · Genomics England PanelApp · Autosomal dominant · 2021
Where it sits
Other names
3 names
Resolves to: chondrosarcoma
- Also called
- chondrosarcoma (disease)chondrosarcoma, malignantchondrosarcoma, somatic mutation