autosomal dominant slowed nerve conduction velocity
Findings
No curated finding names autosomal dominant slowed nerve conduction velocity yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Autosomal dominant slowed nerve conduction velocity is a hereditary demyelinating motor and sensory neuropathy characterized by slowed nerve conduction velocities, in the absence of clinically apparent neurological deficits, gait abnormalities or muscular atrophy, associated with a germline mutation in the ARGHEF10 gene.
Definition from the Mondo Disease Ontology (MONDO:0011998), read 2026-09-29. CC BY 4.0.
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- ARHGEF10HGNC:14103
- Moderate · PanelApp Australia · Autosomal dominant · 2025
- Supportive · Orphanet · Autosomal dominant · 2021
- Limited · ClinGen · Autosomal dominant · 2026
- Limited · Labcorp Genetics (formerly Invitae) · Unknown · 2017
Where it sits
Other names
1 name
Resolves to: autosomal dominant slowed nerve conduction velocity
- Also called
- slowed nerve conduction velocity, AD