autosomal dominant nonsyndromic hearing loss 58
Findings
No curated finding names autosomal dominant nonsyndromic hearing loss 58 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
An autosomal dominant nonsyndromic deafness that has material basis in variation in the chromosome region 2p21-p12.
Definition from the Mondo Disease Ontology (MONDO:0014293), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Juvenile onset · Young adult onset · Childhood onset
HPO, annotations 2026-09-02
Features
3 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Sensorineural hearing impairmentHPOHP:0000407
- 20 of 20 reported patients
- TinnitusHPOHP:0000360
- 15 of 19 reported patients
- Reduced visual acuityHPOHP:0007663
- 0 of 20 reported patients
Genes
2 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.