atrial fibrillation, familial, 18
Findings
No curated finding names atrial fibrillation, familial, 18 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any familial atrial fibrillation in which the cause of the disease is a mutation in the MYL4 gene.
Definition from the Mondo Disease Ontology (MONDO:0015001), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Young adult onset
HPO, annotations 2026-09-02
Features
6 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- First degree atrioventricular blockHPOHP:0011705
- 3 of 6 reported patients
- PalpitationsHPOHP:0001962
- 3 of 6 reported patients
- Permanent atrial fibrillationHPOHP:0004754
- 3 of 6 reported patients
- Paroxysmal atrial fibrillationHPOHP:0004757
- 2 of 6 reported patients
- BradycardiaHPOHP:0001662
- 1 of 6 reported patients
- Third degree atrioventricular blockHPOHP:0001709
- 1 of 6 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- MYL4HGNC:7585
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2021
Where it sits
- A kind of
Other names
5 names
Resolves to: atrial fibrillation, familial, 18
- Also called
- ATFB18atrial fibrillation, familial, 18; ATFB18atrial fibrillation, familial, type 18familial atrial fibrillation caused by mutation in MYL4MYL4 familial atrial fibrillation