arterial calcification of infancy
Findings
No curated finding names arterial calcification of infancy yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Idiopathic arterial calcification of infancy is a rare condition characterized by extensive calcification and stenosis of the large and medium sized arteries.
Definition from the Mondo Disease Ontology (MONDO:0018870), read 2026-09-29. CC BY 4.0.
Features
59 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Arterial calcificationHPOHP:0003207
- Very frequent (80% to 99% of cases)
- Calcification of the aortaHPOHP:0004963
- Very frequent (80% to 99% of cases)
- Generalized arterial calcificationHPOHP:0004940
- Very frequent (80% to 99% of cases)
- Hepatic calcificationHPOHP:0006559
- Very frequent (80% to 99% of cases)
- Coronary artery calcificationHPOHP:0001717
- Frequent (30% to 79% of cases)
- CyanosisHPOHP:0000961
- Frequent (30% to 79% of cases)
- Ectopic calcificationHPOHP:0010766
- Frequent (30% to 79% of cases)
- Feeding difficultiesHPOHP:0011968
- Frequent (30% to 79% of cases)
- Fetal distressHPOHP:0025116
- Frequent (30% to 79% of cases)
- Hearing impairmentHPOHP:0000365
- Frequent (30% to 79% of cases)
- HypertensionHPOHP:0000822
- Frequent (30% to 79% of cases)
- Hypophosphatemic ricketsHPOHP:0004912
- Frequent (30% to 79% of cases)
Show the remaining 47
- Left ventricular systolic dysfunctionHPOHP:0025169
- Frequent (30% to 79% of cases)
- Medial calcification of large arteriesHPOHP:0004966
- Frequent (30% to 79% of cases)
- Medial calcification of medium-sized arteriesHPOHP:0012457
- Frequent (30% to 79% of cases)
- Medullary nephrocalcinosisHPOHP:0012408
- Frequent (30% to 79% of cases)
- NephrocalcinosisHPOHP:0000121
- Frequent (30% to 79% of cases)
- OsteomalaciaHPOHP:0002749
- Frequent (30% to 79% of cases)
Genes
2 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
Where it sits
- A kind of
Other names
6 names
Resolves to: arterial calcification of infancy
- Also called
- generalised arterial calcification of infancyGeneralized Arterial Calcification of Infancyidiopathic infantile arterial calcificationidiopathic obliterative arteriopathyinfantile arteriosclerosisocclusive infantile arteriopathy