amyotrophic lateral sclerosis-parkinsonism-dementia complex
MONDO:0007104Mondo
Findings
No curated finding names amyotrophic lateral sclerosis-parkinsonism-dementia complex yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Late onset · Middle age onset
HPO, annotations 2026-09-02
Features
4 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Cerebral atrophyHPOHP:0002059
- 1 of 3 reported patients
- DementiaHPO · MondoHP:0000726
- 1 of 3 reported patients
- ParkinsonismHPO · MondoHP:0001300
- 0 of 3 reported patients
- Amyotrophic lateral sclerosisHPOHP:0007354
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- TRPM7HGNC:17994
- Limited · Labcorp Genetics (formerly Invitae) · Unknown · 2020
- Limited · PanelApp Australia · Autosomal dominant · 2025
Where it sits
- A kind of
Other names
4 names
Resolves to: amyotrophic lateral sclerosis-parkinsonism-dementia complex
- Also called
- amyotrophic lateral sclerosis-Parkinsonism/dementia Complex type 1Guam diseaseLytico-Bodig diseaseLytigo-Bodig disease